Table 2. Association between tagSNPs on TERT and CLPTM1L region and GIST risk (Stage I).
| SNP | Allelesa | MAFb | AB OR (95% CI) | BB OR (95% CI) | B vs A OR (95% CI) | P |
|---|---|---|---|---|---|---|
| rs7726159 | C/A | 0.33 | 1.32 (0.93–1.87) | 1.67 (1.04–2.68) | 1.33 (1.05–1.69) | 0.017 |
| rs2853677 | A/G | 0.41 | 0.94 (0.66–1.34) | 1.72 (0.41–1.24) | 0.89 (0.71–1.13) | 0.894 |
| rs2736098 | C/T | 0.37 | 1.49 (1.03–2.14) | 1.78 (1.17–2.72) | 1.44 (1.14–1.81) | 1.92 × 10−3 |
| rs13172201 | C/T | 0.25 | 1.18 (0.82–1.69) | 1.24 (0.75–2.05) | 1.17 (0.90–1.50) | 0.241 |
| rs10069690 | C/T | 0.16 | 1.36 (0.96–1.93) | 2.82 (0.91–8.74) | 1.40 (1.04–1.88) | 0.025 |
| rs451360 | C/A | 0.14 | 1.13 (0.76–1.69) | 1.52 (0.69–3.33) | 1.22 (0.89–1.68) | 0.222 |
a
Major/minor alleles as determined by allele frequency among genotyped controls
b
Minor allele frequency among genotyped controls
AA: major allele homozygotes (reference group); AB: heterozygotes; BB: minor allele homozygotes; A: major allele; B: minor allele
P value in bold means statistically significant.