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. 2015 Sep 7;6(31):31368–31377. doi: 10.18632/oncotarget.5187

Figure 1. In vitro efficacy of S. typhimurium A1-R-GFP on HT-29-RFP colon cancer cells.

Figure 1

AC. Confocal imaging of HT-29-RFP cells with S. typhimurium A1-R-GFP over time with the FV1000 confocal microscope. S. typhimurium A1-R infection of HT-29-RFP cells at one hour after administration (B) At 15 hour after administration, more bacterial cells were visualized in cancer cells (C). Arrows show infecting S. typhimurium A1-R expressing GFP. S. typhimurium A1-R inhibited cell proliferation both in colony area D. and number E. **P < 0.01. Error bars: ± 1 SE. Scale bars: 20 μm (BF, bright-field). The cells in Figures 1A, B and C were chosen as before and after examples of infection with S. typhimurium A1-R-GFP, not to indicate efficacy, which occurs at later times.