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. 2015 Sep 8;6(31):31493–31507. doi: 10.18632/oncotarget.5154

Figure 6. ITGA9 is differentially hypermethylated in NPC clinical samples.

Figure 6

Methylation status of two subsets of CpG dinucleotides present in one CpG-rich region in ITGA9 gene promoter investigated by sequencing the bisulfite converted DNA using two pyrosequencing assays. Pyro-S1 and pyro-S2 contained four and three CpG sites respectively (see figure 4B). Open and filled circles represent unmethylated and methylated CpG sites, respectively. Circles are filled according to the fraction of sequences methylated at the CpG sites.