Table 2. Comparisons table and log-rank test for prognostic factor categories.
POPULATION [K-Ras mutated codons] |
PFS (95%CI) [mts] |
OS (95%CI) [mts] |
---|---|---|
Codon 12, all patients (pts) |
8.25 (95%CI: 7.48-9.01) | 28 (95%CI: 23.67-32.32) |
Codon 12, pts with >40% vs ≤40% mutant alleles |
7.45 (95%CI: 5.78-9.21) vs 9.45 (95%CI: 8.47-10.4) | 23 (95%CI: 19.79-26.20) vs 31 (95%CI: 27.00-34.99) |
Codon 13, all pts |
8.90 (95%CI: 7.69-10.10) | 21 (95%CI: 16.63-25.36) |
Codon 13, pts with >40% vs ≤40% mutant alleles |
7.25 (95%CI: 3.6-10.89) vs 10.25 (95%CI: 8.15-12.32) | 17 (95%CI: 11.61- 22.78) vs 24 (95%CI: 19.41- 28.58) |
Rare codons, all pts |
5.50 (95%CI: 2.95- 8.04) | 31 (95%CI: 27.03-34.03) |
Rare codons, pts with >40% vs ≤40% mutant alleles |
5.5 (95%CI: 10.75-31.04) vs 7.25 (95%CI: 2.44-12.05) | - |
All K- Ras mutated codons, pts with >40% vs ≤40% mutant alleles |
7.25 (95%CI: 5.76-8.73) vs 9 (95%CI: 7.96-10.03) | 21 (95%CI: 18.35-23.64) vs 31 (95%CI: 26.66-35.33) |
Log-Rank P | P=0.000 | P=0.002 |