Skip to main content
. 2015 Aug 28;6(31):31659–31673. doi: 10.18632/oncotarget.5229

Figure 6. SMAD2 and SMAD3 are required for the up-regulation of integrin β3 by activin B.

Figure 6

HEC-1B and KLE cells were transfected for 48 h with 20 nM control siRNA (si-Ctrl), SMAD2 siRNA (si-SMAD2) or SMAD3 siRNA (si-SMAD3) and then treated without (Ctrl) or with 50 ng/mL activin B (Act B) for 24 h. Integrin β3, SMAD2 and SMAD3 mRNA A. and protein B. levels were measured by RT-qPCR and Western blot, respectively. Results are expressed as the mean ± SEM of at least three independent experiments. Values without a common letter are significantly different (P < 0.05).