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. 2015 Aug 28;6(31):31659–31673. doi: 10.18632/oncotarget.5229

Figure 7. Integrin β3 mediates activin B-induced endometrial cancer cell migration, invasion and adhesion to vitronectin.

Figure 7

A., HEC-1B and KLE cells were transfected for 48 h with 20 nM control siRNA (si-Ctrl) or integrin β3 siRNA (si-β3) and knockdown efficiencies were examined by RT-qPCR and Western blot. Migration B., invasion C. and vitronectin adhesion D. assays were performed with HEC-1B and KLE cells following transfection with 20 nM control or integrin β3 siRNA for 48 h prior to treatment without (Ctrl) or with 50 ng/mL activin B (Act B) for a further 24 h. Results are expressed as the mean ± SEM of at least three independent experiments. Values without a common letter are significantly different (P < 0.05).