Table 1. Relationship between KDM4B/KDM4A expression and clinicopathological features in 76 endometrial cancer tissue samples.
Parameter | No. | KDM4B | p | KDM4A | p | ||
---|---|---|---|---|---|---|---|
High | Low | High | Low | ||||
Age (years) | |||||||
≤55 | 31 | 19 | 12 | 0.183 | 20 | 11 | 0.841 |
>55 | 45 | 34 | 11 | 28 | 17 | ||
FIGO stage | |||||||
I | 58 | 39 | 19 | 0.708 | 36 | 22 | 0.885 |
II | 6 | 4 | 2 | 4 | 2 | ||
III | 11 | 9 | 2 | 7 | 4 | ||
IV | 1 | 1 | 0 | 1 | 0 | ||
Pathological type | |||||||
Endometrioid | 63 | 43 | 20 | 0.743 | 40 | 23 | 1.000 |
Non-endometrioid (serous/clear) | 13 | 10 | 3 | 8 | 5 | ||
Histological grade | |||||||
G1 | 35 | 19 | 16 | 0.029 | 24 | 11 | 0.593 |
G2 | 22 | 19 | 3 | 13 | 9 | ||
G3 | 6 | 5 | 1 | 3 | 3 | ||
Lymph node metastasis | |||||||
Positive | 10 | 7 | 3 | 1.000 | 8 | 2 | 0.308 |
Negative | 66 | 46 | 20 | 40 | 26 | ||
Depth of myometrial invasion | |||||||
≤1/2 | 47 | 28 | 19 | 0.020 | 27 | 20 | 0.227 |
>1/2 | 29 | 25 | 4 | 21 | 8 | ||
ERα expression | |||||||
Positive | 61 | 43 | 18 | 1.000 | 39 | 22 | 0.999 |
Negative | 15 | 10 | 5 | 9 | 6 | ||
P53 expression | |||||||
Positive | 20 | 15 | 5 | 0.588 | 11 | 9 | 0.425 |
Negative | 56 | 38 | 18 | 37 | 19 |