Table 2. Fisher's exact test to determine the clonality between the 1st and the 2nd tumors by evaluating the concordance of their somatic SNVs.
Patient ID | Number of mutationsA | P value | FDR | ||
---|---|---|---|---|---|
Tumor 1 | Tumor 2 | Shared | |||
1 | 40 | 46 | 3 | 0.46 | 0.68 |
2 | 63 | 38 | 7 | 0.05 | 0.10 |
3 | 91 | 81 | 4 | 0.99 | 0.99 |
4 | 28 | 185 | 7 | 0.56 | 0.68 |
5 | 70 | 95 | 64 | 8.80E-44 | 5.28E-43 |
6 | 47 | 89 | 41 | 7.36E-29 | 2.21E-28 |
only exonic mutations were included.
1-4, BBC patients; 5-6,metastatic breast cancer patients.