Table 1. Tumor seeding ability with serial transplantation from drugs-treated HCC cells.
Cells injected | PLC/PRF/5 | Huh7 | ||||
---|---|---|---|---|---|---|
DMSO | Icaritin | Cisplatin | DMSO | Icaritin | Cisplatin | |
5×105 (n=5) | 5/5 | 0/5 | 5/5 | 5/5 | 0/5 | 5/5 |
5×104 (n=5) | 5/5 | 0/5 | 5/5 | 3/5 | 0/5 | 3/5 |
Cells survived from drugs treatment were subcutaneously injected with 5×105 and 5×104 respectively into each of NOD/SCID mice. Tumor incidence was analyzed after 40 days of cells injection.