Table 2. Fourteen HER2-positive and one HER2-negative with HER2 mutation patients.
Sample.ID | ERBB2 | ERBB2 | Mutation | Amplification value | GRB2 mRNA | HER2–3 pathway |
---|---|---|---|---|---|---|
OS191 | Amp. (14.53) | No | 14.53 | 0.674 | 0.447 | |
OS226 | p.P420fs (0.22) | Amp. (13.99) | Yes | 13.99 | 0.144 | −0.591 |
OS230 | Amp. (22.38) | No | 22.38 | 0.897 | 0.178 | |
OS240 | S413L (0.01) | Amp. (16.39) | Yes | 16.39 | 0.431 | −0.136 |
OS244 | Amp. (12.36) | No | 12.36 | 0.286 | −0.037 | |
OS245 | Amp. (16.04) | No | 16.04 | N/A | N/A | |
OS256 | S72A (0.01) | Amp. (25.93) | Yes | 25.93 | N/A | N/A |
OS257 | Amp. (30.13) | No | 30.13 | 1.716 | −0.470 | |
OS265 | Amp. (14.09) | No | 14.09 | 1.189 | −0.156 | |
OS306 | Amp. (13.8) | No | 13.8 | N/A | N/A | |
OS251 | P562S (0) | Amp. (20) | yes | 20 | −0.024 | −0.593 |
OS314 | Amp. (9.52) | No | 9.52 | 1.388 | −0.485 | |
OS321 | Q692X (0.02) | Amp. (5.39) | Yes | 5.39 | 0.541 | −0.206 |
OS337 | Amp. (3.99) | No | 3.99 | 0.301 | 0.040 | |
OS266 | L755S (0.19) | None | Yes | 2 | 0.144 | −0.591 |
*NA: not available