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. 2015 Jul 22;6(31):32193–32204. doi: 10.18632/oncotarget.4975

Figure 2. Decreased XRCC2 expression in pretreatment biopsy tissue samples of LARC patients who received PRT is associated with improved postoperative histological tumor regression and better long-term prognosis.

Figure 2

A. Positive XRCC2 expression in a representative biopsy specimens from a patient who exhibited resistance to PRT. B. Negative XRCC2 expression in a representative biopsy specimen from a patient who exhibited sensitivity to PRT. C. Positive XRCC2 expression in a representative biopsy specimen with poor tumor regression grade (TRG ≤ 2). D. Negative XRCC2 expression in a representative biopsy specimen with good tumor regression grade (TRG ≥ 3). E. Kaplan-Meier plot of overall survival. Survival was significantly improved in patients with XRCC2-negative tumors (blue line) than in patients with XRCC2-positive tumors (green line) (P < 0.01).