Table 1. Transcriptome gene changes in the downregulated mRNA expression of MMPs in response to combination treatment.

Gene	fold change	‘p’ value
MMP 19	24.32	<0.002
MMP 23	21.48	<0.02
MMP 9	18.47	<0.008
MMP 3	12.04	<0.02
MMP 17	11.47	<0.04
MMP 12	10.39	<0.002
MMP28	10.10	<0.002
MMP 11	7.27	<0.02