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. 2015 Sep 10;6(32):33587–33601. doi: 10.18632/oncotarget.5599

Figure 7. HOXA-AS2 promotes tumorigenesis of GC cells in vivo.

Figure 7

A. Empty vector or sh-HOXA-AS2 was transfected into SGC-7901 cells, which were injected in the nude mice (n = 6), respectively. Tumors formed in sh-HOXA-AS2 group were dramatically smaller relative to controls. B. Tumor volumes were calculated after injection every three days. Points, mean (n = 6); bars indicate SD. C. Tumor weights were represented as means of tumor weights ± SD. D. QRT-PCR was performed to detect the average expression of HOXA-AS2 in xenograft tumors (n = 6). E. The tumor sections were under H&E staining and IHC staining using antibodies against ki-67 and P21. F. correlation analysis revealed that HOXA-AS2 expression levels were inversely correlated with P21 expression levels in GC gene expression dataset GSE15459. Error bars indicate mean ± standard errors of the mean. *P < 0.05, **P < 0.01.