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. 2015 Sep 16;6(32):33733–33742. doi: 10.18632/oncotarget.5254

Figure 3. Compounds 1, XYIMSR-01 and [113/115In]XYIMSR-01 demonstrate high binding affinity to CAIX.

Figure 3

IC50 values of positive control CAIX targeting agent 1 A. XYIMSR-01 B. and [113/115In]XYIMSR-01 C. were determined relative to the inhibition of fluorescence polarization of FITC labeled 8 with a known Kd of 0.2 nM for CAIX [27].