Table 1. Correlation between lncRNA DBH-AS1 expression and clinicopathological characteristics in HCC patients (n=45).
| Variables | lncRNA DBH-AS1 expression | x2 | *P Value | |
|---|---|---|---|---|
| Low | High# | |||
| All cases | 22 | 23 | ||
| Age | 0.218 | 0.641 | ||
| >55 | 9 | 11 | ||
| <=55 | 13 | 12 | ||
| Gender | 0.505 | 0.477 | ||
| Male | 19 | 18 | ||
| Female | 3 | 5 | ||
| HBsAg | 4.132 | 0.042* | ||
| positive | 12 | 19 | ||
| negative | 10 | 4 | ||
| Liver cirrhosis | 1.779 | 0.182 | ||
| with | 10 | 15 | ||
| without | 12 | 8 | ||
| AFP(ng/ml) | 0.192 | 0.661 | ||
| >20 | 11 | 10 | ||
| <=20 | 11 | 13 | ||
| Tumor size(cm) | 8.006 | 0.005** | ||
| >5cm | 7 | 17 | ||
| <=5cm | 15 | 6 | ||
| Tumor number | 0.505 | 0.477 | ||
| solitary | 19 | 18 | ||
| multiple | 3 | 5 | ||
| Edmondson grade | 0.67 | 0.413 | ||
| I+II | 2 | 4 | ||
| III | 20 | 19 | ||
#
The median expression level was used as the cutoff. Low expression of lncRNA DBH-AS1 in 22 patients was classified as values below the 50th percentile. High lncRNA DBH-AS1 expression in 23 patients was classified as values at or above the 50th percentile.
*
For analysis of correlation between lncRNA DBH-AS1 levels and clinical features,Pearson's chi-square tests were used. *, P <0.05; **, P<0.01.