Figure 5. Tumor onset is delayed in MMTV-MDA-7/MMTV-Erbb2 compound transgenic mice.
A. Schematic of generation of MMTV-MDA-7/MMTV-Erbb2 compound transgenic mice. MMTV-MDA-7 hemizygous mice were mated with MMTV-Erbb2 homozygous mice. B. Kaplan Meier analysis showing delay in tumor onset in MMTV-MDA-7/MMTV-Erbb2 compound transgenic mice. C. Immunohistochemistry showing H&E staining and MDA-7/IL-24 expression in tumor sections of MMTV-Erbb2 and MMTV-MDA-7/MMTV-Erbb2 mice. Yellow bars = 100 μm, white bars = 20 μm. ***, p < 0.001.