Table 1. Characteristics of study subjects in the entire cohort.

Characteristic	SAD (n=459)	Controls (n=751)	P value
Age at examinationa, mean ± SD, yr	71.2±9.6	72.7 ± 5.9	0.004
Age at onset, mean ± SD, yr	68.5±9.7
Age at onset <65, n (%)	161(35.1)
Age at onset ≥65, n (%)	298(64.9)
Sexa, n (%)			0.407
Male	228(49.7)	354(47.1)
Female	231(50.3)	397(52.9)
MMSE score, mean±SD	14.7±6.6	25.1±3.5	<0.001
Missing	1
APOE, n (%)			<0.001
APOE ε4 carriers	190 (41.4)	150 (20.0)
Non-APOE ε4 carriers	269 (58.6)	601 (80.0)

Abbreviation: SAD, Sporadic Alzheimer's disease; MMSE, Mini-mental state examination; SD, Standard deviation.

^aFrequency matched