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. 2015 Oct 12;6(35):36984–36997. doi: 10.18632/oncotarget.6100

Figure 4. Dose-dependent effect of AA, NG, and their combination on inhibition of renal fibrosis in a mouse model of UUO.

Figure 4

a. Dose-dependent responses of AA in inhibition of collagen I expression by Western blot analysis. b. Dose-dependent responses of NG in inhibition of collagen I expression by Western blot analysis. c. LDH release assay for determination of the toxicity of AA (5mg/kg), NG (50mg/kg), and their combination in groups of 4 normal mice. Data represent the mean ± SEM for groups of 4 mice. **p < 0.01, ***p < 0.001 compared to sham-operated mice. #p < 0.05, ##p < 0.01 compared to DMSO-treated UUO mice.