Table 2. Correlations between RPL15 expression and clinicopathologic features in Renji cohort 2 patients with pancreatic ductal adenocarcinoma (PDAC).
| Expression of RPL15 | ||||
|---|---|---|---|---|
| Clinicopathological feature | Total 205 | Low (n=103, 50.2%) | High (n=102, 49.8%) | P value (χ2 test) |
| Age(years) | ||||
| <65 | 97 | 48 (49.5) | 49 (50.5) | 0.837 |
| ≥65 | 108 | 55 (50.9) | 53 (49.1) | |
| Gender | ||||
| Male | 117 | 60 (51.3) | 57 (48.7) | 0.732 |
| Female | 88 | 43 (48.9) | 45 (51.1) | |
| Tumor location | ||||
| Head | 139 | 71 (51.1) | 68 (48.9) | 0.729 |
| Body/tail | 66 | 32 (48.5) | 34 (51.5) | |
| TNM stage(AJCC) | ||||
| Stage I | 38 | 11 (28.9) | 27 (71.1) | 0.033 |
| Stage II | 132 | 71 (53.8) | 61 (46.2) | |
| Stage III | 21 | 13 (61.9) | 8 (38.1) | |
| Stage IV | 14 | 7 (50.0) | 7 (50.0) | |
| Tumor size | ||||
| ≤2cm | 27 | 12 (44.4) | 15(55.6) | 0.518 |
| >2cm | 178 | 91 (51.1) | 87 (48.9) | |
| T classificattion | ||||
| T1,2 | 42 | 15(35.7) | 27 (64.3) | 0.035 |
| T3,4 | 163 | 88 (54.0) | 75(46.0) | |
| Lymph node metastasis | ||||
| Absent | 136 | 63 (46.3) | 73 (53.7) | 0.115 |
| Present | 69 | 40 (58.0) | 29 (42.0) | |
| Distant metastasis | ||||
| Absent | 191 | 96 (50.3) | 95 (49.7) | 0.985 |
| Present | 14 | 7 (50.0) | 7 (50.0) | |
| Vascular invasion | ||||
| Absent | 177 | 84 (47.5) | 93 (52.5) | 0.045 |
| Present | 28 | 19 (67.9) | 9 (32.1) | |
| Histological differentiation | ||||
| Well | 11 | 1 (9.1) | 10 (90.9) | 0.005 |
| Moderate/poor | 194 | 102 (52.6) | 92 (47.4) | |
| CA199 level(U/ml) | ||||
| ≤35 | 26 | 11 (9.1) | 15 (90.9) | 0.627 |
| >35 | 105 | 50 (52.6) | 55 (47.4) | |
| Missing | 74 | |||
Values in parentheses indicate percentage values. The bold number represents the P-values with significant differences.