Skip to main content
. 2015 Sep 22;6(35):37098–37116. doi: 10.18632/oncotarget.5776

Table 2. Specific ubiquitinated proteins known to be degraded by macroautophagy.

Protein Protein types Autophagy receptor E3 ligase Ub chains Ref
AGO2  Native   NDP52 Unkown Unkown [71]
ARTD10  Aggregates   p62 Unkown Unkown [72]
DICER1  Native   NDP52 Unkown Unkown [71]
Dvl2  Aggregates   p62 VHL K63 [73]
HIF2A  Aggregates   p62 VHL Unkown [74]
HTT  Aggregates   TOLLIP Rsp5 K48 and K63 [64]
NFKBIA  Aggregates   p62 Unkown Unkown [75]
p53  Aggregates   p62 MDM2 K63 [70]
p65  Aggresomes   p62 Unkown Unkown [76]
RHOA  Native   p62 Unkown Unkown [77]
TFRC  Native   OPTN Unkown Unkown [78]