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. 2015 Oct 8;6(35):37782–37791. doi: 10.18632/oncotarget.5622

Figure 5. In vivo toxicity of R11-p53C peptide.

Figure 5

A. Levels of RBC, WBC and CRP from mice injected with R11-p53C or control peptides pretreated 24 hrs by intraperitoneal injection. B. Serum levels of AST, ALT and creatinine from mice injected with R11-p53C (20 mg/kg) or control peptides pretreated 72 hrs by intraperitoneal injection. C. Mice weights were measured at 3 days after injected with R11-p53C or control peptides. D. Spleen weights were measured from mice injected with R11-p53C or control peptides treated for 3 weeks. Means ±SD shown (n ≥ 3). Background levels were 43 ± 14.3 U/l for AST, and 29 ± 4.2 U/l for ALT. ALT, alanine aminotransferase; AST, aspartate aminotransferase; WBC, white blood cell; RBC, red blood cell; CRP, C-reactive protein.