Table 1. The correlations of miR-149 with clinicopathological features of HCC.
Clinicopathologic Variable | n | miR-149 | P | |
---|---|---|---|---|
Low expression | High expression | |||
Agent | ||||
Female | 8 | 5 | 3 | 0.441 |
Male | 87 | 42 | 45 | |
Age(year) | ||||
≤ 60 | 83 | 40 | 43 | 0.511 |
> 60 | 12 | 7 | 5 | |
AFP | ||||
< 20 ng/ml | 28 | 10 | 18 | 0.083 |
≥ 20 ng/ml | 67 | 37 | 30 | |
HBsAg | ||||
Negative | 6 | 4 | 2 | 0.384 |
Positive | 89 | 43 | 46 | |
Liver cirrhosis | ||||
Absence | 64 | 33 | 31 | 0.558 |
presence | 31 | 14 | 17 | |
Tumor size(cm) | ||||
≤ 5 | 38 | 16 | 22 | 0.241 |
> 5 | 57 | 31 | 26 | |
Tumor nodule number | ||||
Solitary | 74 | 36 | 38 | 0.763 |
Multiple(≥2) | 21 | 11 | 10 | |
TNM Stage | ||||
I/II | 42 | 15 | 27 | 0.017 |
III/IV | 53 | 32 | 21 | |
Histological grade | ||||
Well and moderately | 82 | 42 | 40 | 0.393 |
Poorly | 13 | 5 | 8 | |
Distant metastasis | ||||
Absence | 68 | 30 | 38 | 0.047 |
presence | 27 | 18 | 9 |