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. 2015 Sep 25;6(35):37906–37918. doi: 10.18632/oncotarget.5412

Figure 3. Expression of Usp22 at the crypt base does not affect small intestine morphology.

Figure 3

a–d. Global reduction of Usp22 levels does not lead to morphological changes of the small intestine. H&E-stained sections have been assessed regarding to villi length (wt/wt: n = 3; wt/lacZ: n = 3, p = 0.20; lacZ/lacZ: n = 3, p = 0.98), number of crypts per 100 μm (wt/wt: n = 3; wt/lacZ: n = 3, p = 0.85; lacZ/lacZ: n = 4, p = 0.65) and corresponding number of cells per crypt (wt/wt: n = 3; wt/lacZ: n = 3, p = 0.63; lacZ/lacZ: n = 3, p = 0.34). Regarding the morphology no significant differences were detected. Scale bar: 100 μm.

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