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. 2015 Oct 16;6(35):38061–38078. doi: 10.18632/oncotarget.5706

Figure 2. STAT5 regulates CDC25A downstream of FLT3-ITD.

Figure 2

a. MV4-11 (left panel) and MOLM-14 (right panel) cells were treated for 2 hours with STAT5 inhibitor (100 nM). CDC25A, Pim1, and STAT5 protein and phosphorylation levels were analyzed by western blot. b. MV4-11 and MOLM-14 cells were transfected for 24 hours with STAT5A/B siRNA and the impact on CDC25A protein level was analyzed by western blot. These results are representative of three independent experiments. Actin was used as a loading control. ns: non specific.