Table 2. Univariate analysis of risk factors for PFS and OS in 90 newly diagnosed MM patients.
| Prognostic parameters | Median PFS (months) |
P value | Median OS (months) |
P value |
|---|---|---|---|---|
| Del(13q) | 0.019 | 0.071 | ||
| Positive | 16.0 | 26.0 | ||
| Negtive | 29.0 | 55.5 | ||
| Del(17p) | <0.001 | <0.001 | ||
| Positive | 14.0 | 16.0 | ||
| Negative | 29.0 | 55.5 | ||
| Amp (1q21) | 0.013 | 0.042 | ||
| Positive | 18.0 | 26.0 | ||
| Negative | 47.5 | 55.5 | ||
| Cytogenetic abnormality | 0.005 | 0.043 | ||
| High-risk | 20.0 | 23.5 | ||
| Non high-risk | 29.0 | Not reached | ||
| Mir-15a | <0.001 | <0.001 | ||
| <2.35 | 14.0 | 15.0 | ||
| ≥2.35 | 29.0 | 55.0 | ||
| Mir-16-1 | 0.104 | 0.229 | ||
| <3.13 | 20.0 | 55.0 | ||
| ≥3.13 | Not reached | Not reached |
Cytogenetic high-risk: any t(4;14), t(14;16) or del(17p).