Table 4. Mir-15a combined with high β2-MG, high-risk genetic abnormality can further identify the high-risk subgroups in newly diagnosed MM patients.

Subgroups	Median PFS (months)	P value	Median OS (months)	P value
Mir-15a and β2-MG		0.012		0.001
High mir-15a and low β2-MG (n = 26)	Not reached		Not reached
Others (n = 52)	18.0		26.0
Low mir-15a and high β2-MG (n = 8)	15.0		15.0
Mir-15a and genetics high risk		P < 0.001		0.004
High mir-15a and no genetics high risk (n = 51)	29.0		Not reached
Others (n = 22)	20.0		23.5
Low mir-15a and genetics high risk (n = 5)	7.0		21.0