Table 4. Log-Rank Test on DMFS for TNM Stages Split by EBVDNA and SUVmax-N Combination.
| TNM stage | No.of patients (%) | DMFS | |
|---|---|---|---|
| Events (No.) | 3- years' DMFS(%) | ||
| III+IVa-b | 874 | ||
| Low DNA+Low SUVmax-N | 286 (32.7) | 13 | 95.7 (93.2–98.2) |
| Low DNA+High SUVmax-N | 235 (26.9) | 18 | 92.2 (88.7–95.7) |
| High DNA+Low SUVmax-N | 92 (10.5) | 9 | 92.3 (87.8–96.8) |
| High DNA+High SUVmax-N | 261 (29.9) | 48 | 80.1 (74.8–85.4) |
| III | 553 | 43 | 91.9 (89.5–94.3) |
| Low DNA+Low SUVmax-N | 229 (41.4) | 10 | 94.2 (90.1–97.8) |
| Low DNA+High SUVmax-N | 160 (28.9) | 11 | 92.9 (89.1–96.9) |
| High DNA+Low SUVmax-N | 44 (8.0) | 2 | 95.0 (89.1–100) |
| High DNA+High SUVmax-N | 120 (21.7) | 20 | 81.1 (77.2–96.8) |
| IVa-b | 321 | 45 | 86.1 (82.2–90.0) |
| Low DNA+Low SUVmax-N | 57 (17.8) | 3 | 92.7 (82.2–100) |
| Low DNA+High SUVmax-N | 75 (23.4) | 7 | 87.2 (77.2–96.8) |
| High DNA+Low SUVmax-N | 48 (15.0) | 7 | 86.3 (74.2–97.7) |
| High DNA+High SUVmax-N | 141 (43.8) | 28 | 77.0 (69.2–84.8) |
Abbreviations: low DNA defined as <6,220 copies/mL EBV DNA; high DNA defined as ≥6,220 copies/mL EBV DNA; low SUVmax-N defined as<7.75 SUVmax-N; high SUVmax-N defined as ≥7.75 SUVmax-N; DFS = disease free survival; DMFS = distant metastasis free survival; OS = overall survival. P values compared for overall log-rank trend test. Events (No.) = the total number of events that occurred at the last follow-up. Values in parentheses indicate 95% confidence interval ranges