Table 2. Patient-specific chromosomal rearrangements used for ctDNA monitoring.

Patient	SV	Chromosomal Positionsa				GenomicRegionb		Genesc
		ChrA	Position	ChrB	Position
1	T01	17	35126102	1	223988874	-	intragenic	TP53BP2
1	T02	8	40477264	2	152374971	-	intragenic	ZMAT4, NEB
2	D01	3	60342822	3	60388671	∼45 Kb	intragenic	FHIT
2	D02	4	185436839	4	185913887	∼500 Kb	intergenic	−
3	T01	8	93421404	6	13191227	-	intragenic	PHACTR1
3	T02	12	3607669	6	145470434	-	intragenic	PRMT8
4	I01	12	1819278	12	−1870423	∼50 Kb	intragenic	ADIPOR2
4	D02	17	39823076	17	39837384	∼14 Kb	intragenic	JUP

Abbreviations: (SV) Structural Variation; (D) Deletion; (I) Inversion; (T) Translocation; (ChrA) Chromosome A; (ChrB) Chromosome B.

^aChromosomal positions were based on human genome reference sequence (hg19), negative signal indicates sequences aligning to the minus strand.

^bGenomic Region: approximate size (Kb) of genomic regions involved in deletions and inversions; genomic context base on gene annotation.

^cGenes: genes involved in patient-specific chromosomal rearrangements.