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. 2015 Sep 5;6(35):38398–38409. doi: 10.18632/oncotarget.5049

Table 1. Characteristics of studies included in the meta-analysis of breastfeeding and endometrial cancer.

Author(year) Country Study design, age Sample size (cases) RR (95%CI) for highest vs. lowest category Adjustment for covariates
Sugawara et al.(2013) Japan cohort,40–79 19,848(32) 0.31(0.12–0.81) Age, BMI, family history of cancer, education, job status, smoking status, alcohol consumption, time spent walking, total calorie intake, menopausal status, age at menarche, age at first delivery, number of deliveries, history of oral contraceptive drug use, history of hormone replacement therapy
Dossus et al.(2009) Denmark, France, Germany, Greece, Italy, the Netherlands, Norway, Spain, Sweden and United Kingdom cohort,- 302,618(1017) 0.77(0.54–1.11) Age, BMI, physical activity, alcohol, diabetes, smoking status, education
Zucchetto et al.(2009) Italy cc,60/61 1,362(454) 1.33(0.95–1.85) Age, period of interview, BMI, age at menarche, age at menopause, parity, oral contraceptive use, when appropriate
Brinton et al.(2007) Polish cc,20–74 2,476(551) 0.72(0.4–1.2) Age, study site, years of education, age at menarche, number of full-term births, ever use of oral contraceptives, ever use of oral hormones, ever smoking, BMI
Okamura et al.(2006) Japan cc,51.6/49.6 251(155) 0.37(0.17–0.82) Age, BMI, oral contraceptive use
Wernli et al.(2006) China cohort,- 259,640(206) 0.62(0.35–1.09) Age at baseline, number of live births
Xu et al.(2004) China cc,30–69 1,559(754) 0.54(0.33–0.87) Age, BMI, family history of cancer, number of pregnancies, history of abortion, duration of menstruation(Continued )
Herrinton et al.(2001) United States cc,20–54 896(179) 0.95(0.65–1.4)
Newcomb et al.(2000) United States cc,40–79 2,239(586) 0.84(0.52–1.4) Age, smoking status, education, body mass, postmenopausal hormone therapy, parity
Salazar-Martinez et al.(1999) Mexico cc,57.1/54.6 837(85) 0.33(0.17–0.65) Age, hormonal use, number of pregnancies, smoking, diabetes mellitus, hypertension, physical activity, menopausal status, BMI
Hirose et al.(1999) Japan cc,48.5/56.6 26,953(1465) 1.48(0.63–3.49) Age, BMI
Rosenblatt et al.(1995) Australia Israel Chile, China, Philippines, and Thailand cc,- 1,069(136) 0.23(0.08–0.68) Number of pregnancies, age at menarche
Brinton et al.(1992) United States cc,- 702(405) 1.01(0.6–1.6) Age, number of births, years of education, recent weight, oral contraceptive use, menopausal estrogen use
Cusimano et al. (1989) Italy cc,61.7/60.2 480(57) 2.94(0.68–12.5) Unclear
Elwood et al.(1977) United States cc,55–59 2,640(622) 1(0.7–1.5) Age, marital status, parity, age at first birth, age at menarche, age at natural menopause, history of stillbirth or miscarriage