Table 2. Univariate analysis for predictions associated with LRFS, DMFS, RFS and OS in 255 ESCC patients.

Variables	LRFS			DMFS			RFS			OS
	HR	95% CI	P	HR	95% CI	P	HR	95% CI	P	HR	95% CI	P
Gender (male/female)	1.02	0.31–3.37	0.971	1.92	0.78–4.72	0.157	1.81	0.84–3.88	0.129	1.64	0.66–4.06	0.283
Age (≥65 Y/<65 Y)	1.36	0.47–3.93	0.567	1.02	0.53–1.97	0.958	1.04	0.58–1.85	0.895	1.19	0.61–2.32	0.605
Smoking (ever/never)	0.79	0.32–1.93	0.606	1.77	0.89–3.53	0.103	1.46	0.84–2.55	0.184	1.50	0.75–3.00	0.253
Alcohol (ever/never)	0.73	0.35–1.52	0.397	1.39	0.86–2.27	0.182	1.31	0.86–1.99	0.205	1.51	0.89–2.59	0.129
Differentiation (poorly/well and moderately)	0.99	0.38–2.57	0.979	1.47	0.90–2.41	0.128	1.38	0.89–2.15	0.151	1.75	1.05–2.93	0.033
Tumor location (lower/upper and middle)	1.17	0.58–2.35	0.660	1.16	0.77–1.75	0.476	1.20	0.84–1.72	0.315	1.20	0.78–1.86	0.411
Tumor length (>5 cm/≤5 cm)	0.93	0.35–2.42	0.874	1.85	1.16–2.93	0.009	1.66	1.10–2.51	0.017	2.49	1.57–3.94	<0.001
T stage (T3–4/T1–2)	2.40	1.04–5.57	0.041	1.65	1.05–2.60	0.031	1.80	1.20–2.68	0.004	2.82	1.61–4.95	<0.001
N stage (N+/N−)	2.37	1.12–5.02	0.024	2.03	1.32–3.12	0.001	2.15	1.47–3.13	<0.001	2.71	1.67–4.40	<0.001
Plasma fibrinogen levels (High/normal)	1.00	0.48–2.08	0.995	3.03	2.00–4.61	<0.001	2.48	1.73–3.55	<0.001	2.60	1.67–4.04	<0.001

Bold values are statistically significant (P < 0.05).