Table 3. Prognostic factors for LRFS, DMFS, RFS and OS by multivariate Cox regression analysis in 255 ESCC patients.

	LRFS		DMFS		RFS		OS
	HR (95% CI)	P	HR (95% CI)	P	HR (95% CI)	P	HR (95% CI)	P
Differentiation (poorly/well and moderately)	0.987 (0.380–2.566)	0.979	1.469 (0.895–2.413)	0.128	1.381 (0.889–2.146)	0.151	1.834 (1.095–3.073)	0.021
Tumor length (>5 cm/≤5 cm)	0.925 (0.354–2.418)	0.874	1.364 (0.849–2.201)	0.204	1.301 (0.848–1.997)	0.228	1.961 (1.211–3.174)	0.006
T stage (T3–4/T1–2)	1.958 (0.819–4.679)	0.131	1.039 (0.636–1.700)	0.878	1.208 (0.785–1.860)	0.390	1.797 (0.989–3.264)	0.054
N stage (N+/N−)	1.995 (0.920–4.330)	0.081	1.592 (1.010–2.509)	0.045	1.740 (1.170–2.588)	0.006	1.997 (1.203–3.304)	0.007
Plasma fibrinogen levels (High/normal)	0.998 (0.479–2.077)	0.995	2.541 (1.615–4.001)	<0.001	2.002 (1.360–2.946)	<0.001	1.728 (1.070–2.793)	0.025

Bold values are statistically significant (P < 0.05).