Table 2. Circulating miR-21-5p and miR-126-3p levels in T2DM patients with different diabetic complications.

	MiR-21 levels
Diabetes complications	Patients with a specific complication vs. all the other patients	Mean ± SD	p
neuropathy	37 vs. 156	0.21±0.27 vs. 0.34±0.39	0.089
nephropathy	27 vs. 166	0.26±0.28 vs. 0.33±0.39	0.489
chronic renal failure	10 vs. 183	0.39±0.41 vs. 0.31±0.38	0.375
retinopathy	84 vs. 109	0.27±0.30 vs. 0.35±0.43	0.165
lower limb arteriopathy	11 vs. 182	0.37±0.33 vs. 0.31±0.38	0.534
MACE	56 vs. 137	0.46±0.44 vs. 0.26±0.33	<0.001
	MiR-126 levels
neuropathy	37 vs. 156	0.18±0.20 vs. 0.24±0.22	0.122
nephropathy	27 vs. 166	0.20±0.16 vs. 0.23±0.22	0.512
chronic renal failure	10 vs. 183	0.23±0.19 vs. 0.23±0.22	0.993
retinopathy	84 vs. 109	0.23±0.20 vs. 0.23±0.23	0.863
lower limb arteriopathy	11 vs. 182	0.23±0.21 vs. 0.29±0.24	0.351
MACE	56 vs. 137	0.21±0.21 vs. 0.28±0.22	0.032

ANCOVA adjusted for age, sex, and number of complications. Levels lower than 0.05 in bold.