Figure 2. Distribution of mutations in the TERT and DPH3 promoter in primary melanomas, BCCs and SCCs.

The mutations at the two loci occurred together more frequently than per chance with an OR of 3.0 for melanoma (95% CI 1.4 - 6.4, P = 0.006), OR of 3.4 for BCC (95% CI 1.5 - 7.6, P = 0.003) and OR of 4.3 for SCC (95% CI 0.9 - 20.2, P = 0.06). Two-sided P values and relative risk were determined by chi² test.