Table 2. Pathologic features.

Case no.	Growth Pattern	Cell type	Vascular structures	Cytologic atypia	TMR	Necrosis	PNI	Grade*	Immunohistochemistry
									CD31	CD34	Other positive markers
1	Fascicles/sheets	Spindle	n.k.	Marked	13	-	-	2	+	n.k.
2	Fascicles/sheets	Spindle/epithelioid	n.k.	Marked	8	-	-	3	+	n.k.
3	Sheets	Primarily spindle	n.k.	Marked	13	+	-	3	+	+	ERG
4	Interspersed	Primarily spindle	Moderate	Moderate	3	-	-	2	+	n.k.	ERG
5	Fascicles/sheets	Primarily spindle	Moderate	Marked	5	+	-	3	+	+
6	Sheets	Spindle	Moderate	Marked	3	-	-	3	+	+
7	Fascicles	Epithelioid	Focal	Moderate	23	-	-	2	+	+
8	Fascicles	Epithelioid	Focal	Marked	6	-	-	3	+	+
9	Interspersed	Spindle	Moderate	Moderate	4	-	-	2	+	-
10	Sheets	Spindle/epithelioid	Focal	Marked	18	+	+	3	+	n.k.	LIVE-1, Prox-1, podoplanin
11	Interspersed	Epithelioid	n.k.	Marked	8	-	-	3	+	n.k.	ERG
12	Sheets	Epithelioid	Absent	Marked	9	+	+	3	+	n.k.
13	Interspersed	Spindle/epithelioid	n.k.	Moderate	6	-	-	2	+	+
14	Interspersed	Spindle	Extensive	Mild	4	-	-	1	+	+
15	Fascicles	Epithelioid	Focal	Moderate	9	-	-	2	+	n.k.
16	Nodular	Epithelioid	Focal	Moderate	14	+	-	2	+	+
17	Nodular	Spindle	Moderate	Moderate	4	-	-	2	+	+
18	Sheets	Epithelioid	Focal	Marked	15	-	+	3	+	n.k.	ERG
19	Fascicles	Primarily spindle	Moderate	Moderate	4	-	-	n.k.	+	+
20	Fascicles/sheets	Primarily spindle	Moderate	Marked	8	+	+	3	n.k.	+
21	Fascicles/sheets	Epithelioid	Focal	Marked	5	-	-	3	+	+
22	Fascicles/sheets	Primarily spindle	Moderate	Moderate	n.k.	+	-	2	+	+
23	Nodular	Spindle	Moderate	Moderate	6	-	-	2	+	n.k.
24	Fascicles/sheets	Spindle	Moderate	Marked	6	+	-	3	n.k.	+
25	Sheets	Epithelioid	Focal	Marked	n.k.	-	-	3	+	n.k.
26	Interspersed	Spindle	Moderate	Moderate	5	-	-	2	+	n.k.
27	Interspersed	Primarily spindle	Extensive	Moderate	3	-	-	2	+	+
28	Interspersed	Primarily spindle	Moderate	Marked	7	-	-	3	+	-
29	Fascicles/sheets	Spindle	Focal	Marked	4	+	-	3	n.k.	n.k.
30	Fascicles/sheets	Spindle	Moderate	Moderate	n.k.	-	+	2	+	-
31	Fascicles	Spindle	Moderate	Marked	5	+	-	3	+	+
32	Fascicles/sheets	Epithelioid	Moderate	Marked	12	+	+	3	+	n.k.
33	Sheets	Epithelioid	Focal	Marked	12	+	+	3	+	n.k.
34	Interspersed	Primarily spindle	Moderate	Moderate	7	-	-	2	+	n.k.

TMR = tumor mitotic rate per mm²; Grade = histologic grade (1=low, 2=intermediate, 3=high) according to FNCLCC (Fédération Nationale des Centres de Lutte Contre le Cancer) [49]; PNI= perineural invasion; n.k.=not known (either not assessable on available material or not performed).