Table 1. Synopsis of the analyses carried out in the parental and F1 generation.
Parental generation | |
6 weeks post irradiation | Sperm number |
Sperm miRNA profile | |
F1 generation conceived 6 weeks after paternal irradiation | |
0–100 weeks after birth | Medulloblastoma induction |
2 days after birth | DNA damage and repair in cerebellar cells |
2 weeks after birth | GCP proliferation |
4 weeks after birth | Evolution of preneoplastic lesions |
8 weeks after birth | Evolution of preneoplastic lesions |
3 months after birth | DNA damage in spleen and bone marrow cells |