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. 2015 Sep 25;6(34):36156–36171. doi: 10.18632/oncotarget.5392

Figure 3. Changes in MDM2 and MDMX protein expression correlate with EMT in a proportion of paired patient prostate and breast tumors and metastases.

Figure 3

Paired patient samples from primary tumors and LN metastases were stained with the indicated antibodies. LN metastases of CaP A. exhibit a more epithelial phenotype compared to the primary tumor from the same patient. Arrows show cytosolic vimentin staining indicating EMT; asterisk shows vimentin positivity in the stroma. LN metastases of BrCa demonstrate both MET-like B. and EMT-like C. transitions. Magnification: 20×; dashed boxes indicate region in insets at 40× magnification.