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. 2015 Sep 26;6(34):36319–36337. doi: 10.18632/oncotarget.5415

Figure 3. PPARβ/δ inhibits MMP activities and anchorage-independent clonogenicity of human testicular embryonal carcinoma NT2/D1 cells.

Figure 3

A. Left panel, anchorage-dependent clonogenicity of NT2/D1, MigR1 or hPPARβ/δ cells treated with or without GW0742. Right panel, plating efficiency and survival fraction of anchorage-dependent clonogenicity assay. B. Anchorage-independent clonogenicity of MigR1 and hPPARβ/δ cells with or without GW0742. C. Representative photomicrographs of colonies on soft agar (Magnification = 200X). D. Quantification of colonies, diameter of the colonies, and the size of the colonies on soft agar. E. Activities of MMP2 and MMP9 in NT2/D1, MigR1 and hPPARβ/δ cells. Values represent the mean ± S.E.M. Values with different superscript letters are significantly different at p ≤ 0.05. *Significantly different than control, p ≤ 0.05.