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. 2015 Sep 26;6(34):36319–36337. doi: 10.18632/oncotarget.5415

Figure 6. Over-expression of PPARβ/δ decreases testicular cancer cell invasion of a HUVEC monolayer.

Figure 6

Testicular cancer cell-endothelial cell interaction was detected in real-time using an xCELLigence system. NT2/D1 cell lines were seeded on top of HUVEC monolayer, and cell index was recorded up to 8 hours. Over-expression of PPARβ/δ increased the cell index, indicating a suppression of cell invasion through the HUVEC monolayer. No changes in cell index were observed among NT2/D1 cell lines following GW0742 treatment. Values represent mean ± S.E.M. *Significantly different than NT2/D1 cell control, p ≤ 0.05. #Significantly different than the HUVEC negative control, p ≤ 0.05.