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. 2015 Oct 10;6(34):36652–36674. doi: 10.18632/oncotarget.5543

Figure 1. Schematic overview of the gene expression-based sub-classification of histological grade 2 (HG2) samples into HG1-like and HG3-like.

Figure 1

A. The basic concept of HG2 dichotomization based on the pattern recognition analysis supervised by the gene expression of HG1 and HG3 tumors. B. the workflow of our methodology of the sub-classification of HG2 and integrative data analyses of different genetic grades obtained by 22g-TAG classifier of TCGA cohort. DEGs: Differentially Expressed Genes; DAGs: Differentially Altered Genes; HG: Histological grades; SWS: Statistically Weighted Syndrome algorithm; PAM: Prediction Analysis of Microarray algorithm; LGG: Low Genetic Grades; HGG: High Genetic Grades.