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. 2015 Sep 23;6(34):36860–36869. doi: 10.18632/oncotarget.5365

Table 1. The clinico-pathologic characteristics of patients at time of initial diagnosis (n = 235).

Parameters Value
Median age (range) (years) 47 (27–83)
Interval to recurrence from mastectomy (mos) 33.2 (4.5–236)
Menopausal status Pre-
Post-
139 (59.1%)
96 (40.9%)
Location of primary tumor Medial
Central
Outer
88 (37.4%)
12 (5.1%)
135 (57.3%)
Primary tumor histopathology IDC
Others
222 (94.5%)
13 (5.5%)
Primary tumor stage pT1
pT2
pT3
Unknown
76 (32.3%)
139 (59.1%)
15 (6.4%)
5 (2.1%)
Tumor grade 1
2
3
17 (7.2%)
114 (48.5%)
104 (44.3%)
No. of nodes removed 12 (6–30)
Nodal stages pN0
pN1
pN2
pN3
129 (54.9%)
79 (33.6%)
19 (8.1%)
8 (3.4%)
ER status Positive
Negative
149 (63.4%)
86 (36.6%)
PR status Positive
Negative
130 (55.3%)
105 (44.7%)
HER2 status 0~+
++
+++
167 (71.1%)
32 (13.6%)
36 (15.3%)
Biologic subtype Luminal A
Luminal B
Luminal HER2
HER2
Triple negative
83 (35.3%)
58 (24.7%)
23 (9.8%)
22 (9.4%)
49 (20.9%)
Primary surgery MRM
Others
204 (86.8%)
31 (13.2%)
Initial systemic therapy Chemotherapy only
Endocrine therapy only
Chemotherapy + endocrine therapy
Trastuzumab
None
88 (37.4%)
11 (4.7%)
130 (55.3%)
3 (1.3%)
6 (2.6%)

Abbreviations: ILRR = isolated locoregional recurrence; IDC = invasive ductal carcinoma; ER = estrogen receptor; PR = progesterone receptor; HER2 = human epidermal growth factor receptor 2; MRM = modified radical mastectomy