Table 1. Challenge of DENV clinical isolates in IFN-α/β/γR KO mice.
Virus | Titer (FFU) | Number a | % Survival | Period b |
---|---|---|---|---|
DV3-2 | 3.3×105 | 4 | 100 | -c |
DV3-3 | 3.1×105 | 5 | 100 | -c |
DV3-4 | 8.3×105 | 5 | 40 | 25–32 |
P12/08 | 2.0×105 | 3 | 0 | 9–24 |
a Numbers of mice used for challenge.
b Period indicates the days when mice condition reached the end point.
c All mice survived until days 42 post-infection without symptom.