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Knee diameter in mice. Knee joint diameters, measured 4 h following intra‐articular injection of neutrophil elastase, showing a significant increase in wild‐type mice, but not in PAR2 KO mice (PAR 2−/−), when compared with intra‐articular saline. Values represent mean ± SEM (n = 9–15/group). *P < 0.05, ***P < 0.001 compared with neutrophil elastase.
