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. 2015 Jun 19;10(1):11–18. doi: 10.4162/nrp.2016.10.1.11

Fig. 5. Effects of D-xylose on 2-NBDG uptake by C2C12 cells and insulin secretion by INS-1 pancreatic β-cells.

Fig. 5

The effect of glucose (A) or D-xylose (B) on 2-NBDG uptake by C2C12 skeletal muscle cells was assayed. Cells were treated with 100 nM insulin, Xylo 5, or Xylo 10, and 2-NBDG uptake assays were performed (see Materials and Methods). The effect of glucose (C) or D-xylose (D) on insulin secretion by INS-pancreatic β-cells was analyzed. The values shown are the mean ± SEM. Letters are used to indicate the values that significantly differ from each other (P < 0.05). Ins, insulin (a positive control); Glu, glucose; Xylo 5 or Xylo 10, treatment with 5% or 10% of the total glucose content of media was replaced with D-xylose