Table 1.
CGN+MDA | NWH | |
---|---|---|
Total pedigrees | 2713 | 1344 |
Probands of AJ descent: n (%) | 744 (27.4) | 366 (27.2) |
Probands tested BRCA1+: n (%) | 377 (13.9) | 49 (3.6) |
Probands tested BRCA2+: n (%) | 202 (7.4) | 76 (5.7) |
No. of members per pedigree: median (IQR) | 20 (15) | 19 (20) |
Age of proband: median (IQR) | 49 (17) | 53 (16) |
Males tested: n (%) | 87 (3.2) | 14 (1) |
Males tested with BC: n (%) | 48 (1.8) | 6 (0.4) |
Probands with unilateral BC: n (%) | 1628 (60) | 698 (51.9) |
Probands with bilateral BC: n (%) | 244 (9) | 72 (5.4) |
Probands with OC: n (%) | 245 (9) | 55 (4.1) |
Probands with BC & OC: n (%) | 88 (3.2) | 17 (1.3) |
BC age for proband: median (IQR) | 43 (14) | 47 (13.75) |
OC age for proband: median (IQR) | 51 (14) | 53 (16.5) |
IQR: Inter-Quartile Range; BC: Breast Cancer; OC: Ovarian Cancer