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. 2016 Jan 12;7(2):141–151. doi: 10.1007/s13238-015-0234-5

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© The Author(s) 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Onco-miR-24 regulates proliferation, apoptosis and migration of GC cells. SGC7901 cells were transfected with miR-24 mimics or inhibitors, and cell growth, apoptosis and migration were evaluated respectively. (A) Overexpression of miR-24 promotes cell proliferation of SGC7901 cells. (B) Knockdown of miR-24 suppress GC cell growth. (C) MiR-24 inhibits cell apoptosis of SGC7901 cells. (D) Quantitative analysis of (C). (E and F) Transwell assays show that miR-24 promotes cell migration of GC cells. (G) Validation of miR-24-mediated cell migration by scraping line method. ** indicates P < 0.01