Table 1.

miRNAs aberrantly expressed and validated target genes in BCSCs

miRNA	Expression	Targets	Function	References
let-7	Down	H-Ras, HMGA2	Reduce BCSCs	Yu et al. (2007)
miR-200c	Down	BMI1	Reduce BCSCs	Shimono et al. (2009)
miR-200b	Down	SUZ12	Reduce BCSCs	Iliopoulos et al. (2010)
miR-93	Down	AKT3, SOX4 and STAT3	Inhibit BCSCs in basal type cancer, promote BCSCs in luminal type cancer	Liu et al. (2012)
miR-100	Down	SMARCA5, SMARCD1 and BMPR2	Inhibit BCSCs	Deng et al., (2014)
miR-141	Down	Stat5a and PR	Reduce BCSCs	Finlay-Schultz et al. (2014)
miR-34c	Down	Notch4	Inhibit BCSCs	Yu et al. (2012)
miR-30	Down	Ubc9 and ITGB3	Inhibit BCSCs	Yu et al. (2010)
miR-128	Down	BMI1 and ABCC5	Inhibit BCSCs	Zhu et al. (2011)
miR-140	Down	ALDH1 and SOX9	Inhibit BCSCs	Zhang et al. (2012)
miR-27a	Down	ZBTB10	Inhibit BCSCs	Tang et al. (2014)
miR-27b	Down	ENPP1	Inhibit BCSCS	Takahashi et al. (2015)
miR-7	Down	KLF4, SETDB1	Inhibit BCSCs	Okuda et al. (2013); Zhang et al. (2014a)
miR-34a	Down	Notch1	Reduce BCSCs	Park et al. (2014)
miR-142	Up	APC	Promote BCSCs	Isobe et al. (2014)
miR-21	Up	PTEN, AKT and ERK1/2 pathways	promote BCSCs	Han et al. (2012a, b, c)
miR-29	Up	Non report	Promote BCSCs	Li et al. (2014)
miR-495	Up	E-Cadherin	Promote BCSCs	Hwang-Verslues et al. (2011)
miR-181	Up	ATM	Promote BCSCs	Finlay-Schultz et al. (2014)
miR-22	Up	TET-family proteins	Promote BCSCs	Song et al. (2013)
miR-221	Up	ATXN1	Promote BCSCs	Ke et al. (2015)
miR-9	Up	Non-report	Promote BCSCs	Gwak et al. (2014)