Table. 1.
Summary of Nectin-1 expression level on neuroblastoma tissue microarray
Clinical Information | Number of Cases | |||||
---|---|---|---|---|---|---|
Histology | Stage | Cell type | 0 | 1+ | 2+ | 3+ |
Neuroblastoma | I | Neuroblast | 5 | 4 | ||
Neuropil | 4 | 3 | ||||
II | Neuroblast | 1 | 4 | 5 | ||
Neuropil | 1 | 1 | 5 | |||
III | Neuroblast | 2 | 5 | |||
Neuropil | 2 | 4 | ||||
IV | Neuroblast | 1 | 3 | 6 | 16 | |
Neuropil | 1 | 4 | 6 | 15 | ||
Ganglioneuroma | N/A | Ganglion | 2 | |||
Ganglioneuroblastoma | Neuroblast | 3 | ||||
Neuropil | 2 | |||||
Tonsil | N/A | N/A | 3 | |||
Total NB cases | 2 | 4 | 17 | 33 | ||
Percentage | 3% | 7% | 30% | 59% |
56 primary neuroblastoma samples were subjected to IHC staining to detect nectin-1 expression. The degree of nectin-1 staining intensity of tumor samples was graded negative as 0, weak as 1+, moderate as 2+, and strong as 3+, by board-certified pathologist, M.H.C