Table 2.
Characteristics of participants at baseline
| Allopurinol (n = 25) | Placebo (n = 25) | P | |
|---|---|---|---|
| Mean age, years | 69.6 (9.1) | 67.3 (7.5) | 0.34 |
| Male sex, n (%) | 21 (84) | 18 (72) | 0.50 |
| Height, m | 1.69 (0.09) | 1.66 (0.07) | 0.28 |
| Weight, kg | 77.7 (16.6) | 80.6 (16.6) | 0.36 |
| BMI | 27.2 (5.1) | 29.1 (5.2) | 0.21 |
| Pulse, beats per minute | 76.5 (11.6) | 75.4 (14.9) | 0.62 |
| Pack-years | 31.7 (21.0) | 49.7 (37.0) | 0.04 |
| Systolic BP, mm Hg | 153 (21) | 156 (20) | 0.65 |
| Diastolic BP, mm Hg | 76 (11) | 79 (10) | 0.27 |
| ABI | 0.61 (0.12) | 0.60 (0.12) | 0.65 |
| Average weekly alcohol intake (units per week) | 7.4 (10.0) | 16.8 (18.8) | 0.08 |
| Smoking status | |||
| Current smoker | 6 | 7 | 0.75 |
| Ex- or nonsmoker | 19 | 18 | |
| Uric acid, mmol/L | 0.36 (0.09) | 0.34 (0.09) | 0.98 |
| Concomitant medications, n (%) | |||
| Aspirin/clopidogrel | 24 (96) | 23 (92) | 0.88 |
| Statin | 23 (92) | 24 (96) | 0.88 |
| ACEi/ARB | 17 (68) | 18 (72) | 0.87 |
Data are presented as mean (SD) except where otherwise noted.
ABI, ankle-brachial index; ACEi, angiotensin-converting enzyme inhibitor; ARB, angiotensin receptor blocker; BMI, body mass index; BP, blood pressure.