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. 2016 Feb;70:106–110. doi: 10.1016/j.jclinepi.2015.08.013

Table 3.

Formula for applying GRADE level of evidence from number of downgrades determined using the algorithm

GRADE level of evidence Number of downgrades (derived from objective assessment)
High 0 downgrade
Moderate 1 or 2 downgrades
Low 3 or 4 downgrades
Very low 5 or 6 downgrades

Abbreviation: GRADE, Grading of Recommendations Assessment, Development and Evaluation.