Skip to main content
. 2016 Jan 21;14(4):760–771. doi: 10.1016/j.celrep.2015.12.090

Figure 3.

Figure 3

L-selectin Expression Does Not Affect the Activation or Differentiation of CD8+ T Cells following intraperitoneal or Intranasal Virus Administration

(A and B) Representative plots show (A) percentages of CD69-positive F5/B6 and F5/LΔP CD8+ T cells in mediastinal LN (Med LN) (day 1 p.i. with vaccNP) and (B) percentages of CD69-positive F5B6 and F5L-sel−/− CD8+ T cells in mediastinal LN at day 2 p.i. with H17 influenza virus. Bar charts show means ± SEM.

(C and D) Representative plots show (C) CD44-positive F5/B6 and F5/LΔP at days 5, 8, and 12 p.i. with vaccNP and (D) F5B6 and F5L-sel−/− CD8+ T cells at day (d) 5 p.i. with vaccNP in ovary (thick line), ovdLNs (thin line), and spleen (dashed line). Bar charts show means ± SEM. CD44 median fluorescence intensity (MFI).

(E) Representative plots show CD44-positive polyclonal influenza-specific CD8+ T cells in lungs (thick line) and spleen (dashed line) of B6 and LΔP mice (day 8 p.i. with PR8 influenza virus). Bar chart shows means ± SEM. CD44 MFI.